How to Store Research Peptides
Peptide stability depends heavily on storage. Proper handling preserves a compound's integrity for your research; poor handling can degrade it long before its theoretical shelf life. Storage differs depending on whether the peptide is still lyophilized or has been reconstituted.
Lyophilized (freeze-dried) peptides
In powder form, peptides are at their most stable. General lab practice:
- Long-term: store in a freezer (commonly around −20 °C or colder), sealed and dry
- Short-term: refrigeration is typically sufficient for a brief period
- Always keep them away from light and moisture
Reconstituted peptides
Once dissolved into solution, peptides are far more sensitive:
- Store refrigerated (typically ~2–8 °C)
- Protect from light
- Avoid repeated freeze-thaw cycles — each cycle stresses the peptide; if freezing for longer storage, aliquot first so you thaw only what you need
- Use within the window appropriate for that compound
Factors that degrade peptides
- Heat and temperature swings
- Light exposure
- Contamination (always reconstitute with sterile technique — see our reconstitution guide)
- Repeated freeze-thaw
A simple rule of thumb
Keep lyophilized vials cold, dark, and dry; keep reconstituted vials refrigerated, dark, and undisturbed. Using bacteriostatic water for reconstitution adds a margin against microbial growth for multi-session work.
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